Mechanisms of alternative splicing in neurodegeneration and ageing at University of Sheffield 2025

Mechanisms of alternative splicing in neurodegeneration and ageing at University of Sheffield 2025 is offered for Masters degree in the field of Bioscience. You can apply to this scholarship here. The deadline for the sending your application is Expired. This scholarship is provided by University of Sheffield and the value of this scholarship is Full Funding, Full tuition fees + stipend.

Open for

Open to all citizens.

Degree

Masters

Provided by

University of Sheffield

Deadline

Expired

Scholarship value: Full Funding, Full tuition fees + stipend PhD Research Project: Mechanisms of Alternative Splicing in Neurodegeneration and Ageing Project

Overview

• This PhD project explores how alternative RNA splicing contributes to ageing, neurodegeneration, and anti-ageing therapies, specifically reduced mTOR signaling and dietary restriction (DR).
• Recent findings have linked alternative splicing to rejuvenation effects observed in Drosophila melanogaster under mTOR suppression and DR conditions.
• The project will manipulate splicing mechanisms, focusing on spliceosome components and specific genes to measure impacts on lifespan, neuronal functioning, and neurodegeneration.

Benefits and Funding

Stipend

A tax-free annual stipend at the UKRI rate (£19,237 for 2024/25). Research Costs & Tuition Fees: Covered at the UK rate.

Duration: 4 years, fully funded. Training: Extensive training in experimental biology, functional genetics, and quantitative analysis.

Eligibility Criteria

• Open to both UK (home) and international (including EU) students.
• Candidates should have (or expect to gain) at least an upper second-class honours degree or equivalent in biological, chemical, physical science, or mathematics disciplines.
• International students should check if they meet entry requirements for their country.
• Full studentships are available for outstan

Open to both UK (home) and international (including EU) students.

Candidates should have (or expect to gain) at least an upper second-class honours degree or equivalent in biological, chemical, physical science, or mathematics disciplines.

International students should check if they meet entry requirements for their country.

Full studentships are available for outstanding international applicants on a competitive basis.

How to Apply

To apply, submit an Expression of Interest form by 5 pm, Friday, 14th March 2025. You can apply for up to three YBDTP projects across different universities.